Alpha-glucosidase inhibition and molecular docking studies of 1, 2-benzothiazine 1, 1-dioxide based carbohydrazides.

FA Saddique, M Ahmad, UA Ashfaq… - Pakistan Journal of …, 2019 - search.ebscohost.com
Diabetes mellitus is a chronic disease in which the infected cells do not have the ability to
produce sufficient amount of insulin that results in the abnormality of carbohydrates
metabolism and an increase in blood glucose level. Long time exposure to diabetes mellitus
results in failure or dysfunction of different organs like kidneys, nerves, heart, eyes, etc. A
common practice to cure diabetes is the use of a-glucosidase inhibitors which help in
lowering the blood glucose level. We presented 1, 2-benzothiazine 1, 1-dioxide derivatives …
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